Dermatology Exams Tips and Tricks

  Important points for MCQs SJS /TEN keratinocyte death is due to apoptosis IVIG in TEN-> blocks Fas mediated keratinocyte death Butcher cut neck - so warts HPV 2/7 Commonest cause of EM is Herpes not Drugs Most Carcinogenic is HPV 16 specially periungual SCC Mutation PYRIN -> FMF P55 TNFR mutation-> TRAPS MAX NBUVB session 300 (48h gap -> 3/wk) PUVA 200 -250(72h gap-> 2/Wk) leukotriene inhibitors associated with chrug strauss Baxarotene given in MF 2b and above BCC location sequence men women Atropine make Mastocytosis worse Lipschutz vulval ulcer -young girls painful/ EBV or reactive after infections Bliateral / kissing- heterophile abs + Rx pain and CS Papular/ urticarial variant of P rosea in children Papular in pregnancy Acyclovir then erythromycin Orf large lesions excised. then cryo /imiquimod/cidofovir Overall mortality from TEN is 50% red burning syndrome is due to topical CS withdrawl some say give oral Cs and tetracycline and isotretinoin as rosacea Kawask...

 IMPORTANT SYNDROMES FOR MCQs Acrodermatitis Enteropathica  Autosomal Recessive SLC39A4 Scaly eczematous plaques over the perioral,perineal, and acral areas-hands /feet  AEC Syndrome (Hay-Wells Syndrome)  Autosomal Dominant P63 -tumor protein- TP long arm of chromosome 3- Erosive scalp dermatitis, 80% cleft lip/palate, ankyloblepharon, hypotrichosis  Albinism , Oculoculaneous Type 1  Autosomal Recessive , TYR -tyrosinase- Severe nystagmus, increased SCC risk. Pink nevi  Albinism, Oculocutaneous Type 2  Autosomal Recessive - P protein defect- Nystagmus, light brown hair, pigmented nevi  Albinism, Oculocutaneous Type 3  Autosomal Recessive TRP- 1 -tyrosinase related protein- Nystagmus, blue/brown iris. Light brown hair/skin  Albright Hereditary Osteodystrophy  Autosomal Dominant GNAS I - encodes a subunit for stimulatory G protein of adenylate cyclase: Gs- Pseudohypoparathyroidism, short stature, shortened fourth metacarpal, sof...